On Exchange 2013 you might encounter a blank page after the login page of the Exchange ECP portal. The Login page will load without issues but when you login successfully, an empty blank page loads.

This could be due to the Default Website and Exchange Back End website do not have the same certificate. Sometimes this happens when you either change the certificate or renew it.

To solve this, open the Internet Information Services (IIS) Manager
Expand Sites
Right click on Default Website and click on Edit Bindings

From the list click on the https with the port 443 cnad click the edit button and confirm that you have the new cerficate selected and take note of it.

Right click on Exchange Back End site and click on Edit Bindings

From the list click on the https with the port 444 and click the edit button. Here make sure that you have the same certificate assigned and click close. In my case the certificate assigned was empty as the certificate was deleted.

Run IISReset from the command prompt as Admin

The ECP will now load.