When opening Outlook you can be presented with the error Cannot open your default e-mail folders. The information store could not be opened. To fix the issue follow the below steps.

– Close Outlook
– Open C:\Program Files (x86)\Microsoft Office\Office14 folder or the folder where Outlook.exe is located.
– Right click on Outlook.exe and select properties.
– On the Compatibility Mode tab
– Un-tick the option Run this program in compatibility mode.
– Open Outlook

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